I've been following Derek Thompson's grappling with these themes over the past few years, and here he tries to unite them in one piece on the "Tragic Twenties": how so many things have come together to create a rogue wave of American unhappiness despite some relatively solid economic figures.
If America's So Rich, How'd It Get So Sad?
Or: How the 2020s broke our brains
derekthompson.org